Synthesis and bioactivity of new analogue of Bicyclic 1-Azafagomine

New (S)-(1,2,3,6-tetrahydropyridazin-3-yl)methanol was synthesized by Lewis acid catalyzed and self-assembled Diels-Alder (LACASA-DA) cycloaddition reaction using (S)-BINOL as a chiral inductor. The N-2 pyridazine position was protected, the hydroxyl group was carbonylated to form the new bicyclic s...

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Bibliographic Details
Main Author: Akhundova, Fidan N. (author)
Other Authors: Kurbanova, Malahat M. (author), Huseynzada, Alakbar E. (author), Alves, Maria José Chão (author), Sujayev, Afsun R. (author)
Format: article
Language:eng
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/1822/73402
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/73402