Mitochondrial permeability transition induced by the anticancer drug etoposide

Etoposide (VP-16) is widely used for the treatment of several forms of cancer. The cytotoxicity of VP-16 has been assigned to the induction of apoptotic cell death but the signaling pathway for VP-16-induced apoptosis is essentially unknown. There is some evidence that this process depends on events...

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Bibliographic Details
Main Author: Custódio, J. B. A. (author)
Other Authors: Cardoso, C. M. P. (author), Madeira, V. M. C. (author), Almeida, L. M. (author)
Format: article
Language:eng
Published: 2001
Subjects:
Etoposide
Anticancer
Apoptosis
Liver mitochondria
Mitochondrial permeability transition
Online Access:http://hdl.handle.net/10316/5799
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5799

Internet

http://hdl.handle.net/10316/5799

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