Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection.

Bacterial pathogens often interfere with host tyrosine phosphorylation cascades to control host responses and cause infection. Given the role of tyrosine phosphorylation events in different human infections and our previous results showing the activation of the tyrosine kinase Src upon incubation of...

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Bibliographic Details
Main Author: Almeida, MT (author)
Other Authors: Mesquita, FS (author), Cruz, R (author), Osório, H (author), Custódio, R (author), Brito, C (author), Vingadassalom, D (author), Martins, M (author), Leong, JM (author), Holden, DW (author), Cabanes, D (author), Sousa, S (author)
Format: article
Language:eng
Published: 2015
Subjects:
Amino Acid Sequence
Bacterial Load
Caco-2 Cells
Enzyme Activation
HeLa Cells
Host-Pathogen Interactions
Humans
Listeria monocytogenes/physiology
Listeriosis/enzymology
Listeriosis/microbiology
Nonmuscle Myosin Type IIA/metabolism
Phosphorylation
Protein Processing, Post-Translational
src-Family Kinases/metabolism
Online Access:http://hdl.handle.net/10216/114511
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/114511

Internet

http://hdl.handle.net/10216/114511

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