T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1

The T cell-surface glycoprotein CD6 is a modulator of cellular responses and has been implicated in several autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and psoriasis. During Ag presentation, CD6 is targeted to the immunological synapse in a ligand binding-dependent manner,...

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Detalhes bibliográficos
Autor principal: Araújo, Mafalda Martins de (author)
Outros Autores: Glória, Vânia G. da (author), Santos, Ana Mafalda (author), Leal, Rafaela (author), Almeida, Sérgio F. de (author), Carmo, Alexandre M. (author), Moreira, Alexandra (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Science & Technology
Texto completo:http://hdl.handle.net/1822/33249
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/33249

Texto Completo

http://hdl.handle.net/1822/33249

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