T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1

The T cell-surface glycoprotein CD6 is a modulator of cellular responses and has been implicated in several autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and psoriasis. During Ag presentation, CD6 is targeted to the immunological synapse in a ligand binding-dependent manner,...

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Bibliographic Details
Main Author: Araújo, Mafalda Martins de (author)
Other Authors: Glória, Vânia G. da (author), Santos, Ana Mafalda (author), Leal, Rafaela (author), Almeida, Sérgio F. de (author), Carmo, Alexandre M. (author), Moreira, Alexandra (author)
Format: article
Language:eng
Published: 2014
Subjects:
Science & Technology
Online Access:http://hdl.handle.net/1822/33249
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/33249

Internet

http://hdl.handle.net/1822/33249

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