Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity
In the present study we have developed lipid nanoparticle (LN) dispersions based on a multiple emulsion technique for encapsulation of hydrophilic drugs or/and proteins by a full factorial design. In order to increase ocular retention time and mucoadhesion by electrostatic attraction, a cationic lip...
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| Other Authors: | , , , , , |
| Format: | article |
| Language: | eng |
| Published: |
2014
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10400.23/576 |
| Country: | Portugal |
| Oai: | oai:repositorio.hospitaldebraga.pt:10400.23/576 |