Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity

In the present study we have developed lipid nanoparticle (LN) dispersions based on a multiple emulsion technique for encapsulation of hydrophilic drugs or/and proteins by a full factorial design. In order to increase ocular retention time and mucoadhesion by electrostatic attraction, a cationic lip...

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Detalhes bibliográficos
Autor principal: Fangueiro, JF (author)
Outros Autores: Andreani, T (author), Egea, MA (author), Garcia, ML (author), Souto, SB (author), Silva, AM (author), Souto, EB (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Texto completo:http://hdl.handle.net/10400.23/576
País:Portugal
Oai:oai:repositorio.hospitaldebraga.pt:10400.23/576