Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation

Purpose: Colorectal tumors (CRC) with microsatellite instability (MSI) show resistance to chemotherapy with 5-fluorouracil (5-FU), the most widely used pharmacological drug for CRC treatment. The aims of this study were to test the ability of quercetin (Q) and luteolin (L) to increase sensitivity of...

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Bibliographic Details
Main Author: Xavier, Cristina P. R. (author)
Other Authors: Lima, Cristóvão F. (author), Rohde, Mikkel (author), Wilson, Cristina Pereira (author)
Format: article
Language:eng
Published: 2011
Subjects:
Apoptosis
Colorectal carcinoma
5-fluorouracil
p53
Quercetin
Science & Technology
Online Access:https://hdl.handle.net/1822/15402
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/15402

Internet

https://hdl.handle.net/1822/15402

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