Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms

Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable mechanisms of response. The present study aimed...

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Bibliographic Details
Main Author: Fonseca, T. G. (author)
Other Authors: Carriço, T. (author), Fernandes, E. (author), Abessa, D. M. S. (author), Tavares, A. (author), Bebianno, M. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Animals
Biotransformation
Bivalvia
DNA damage
Female
Gills
Humans
Male
Oxidative Stress
Tamoxifen
Online Access:http://hdl.handle.net/10400.1/13685
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/13685

Internet

http://hdl.handle.net/10400.1/13685

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