Tamoxifen Inhibits Induction of the Mitochondrial Permeability Transition by Ca2+and Inorganic Phosphate
Tamoxifen (TAM) is a synthetic, nonsteroidal antiestrogenic agent that is widely prescribed in the treatment of estrogen-dependent neoplasias, including breast cancer. The mechanism of action has yet to be defined, but likely is independent of estrogen receptor binding. In light of its high lipophil...
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Other Authors: | , |
Format: | article |
Language: | eng |
Published: |
1998
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Subjects: | |
Online Access: | http://hdl.handle.net/10316/5825 |
Country: | Portugal |
Oai: | oai:estudogeral.sib.uc.pt:10316/5825 |