BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4+IL-17+TNF+IL-2+ T cells

Mycobacterium bovis Bacille Calmette-Guerin (BCG) is the only vaccine in use to prevent Mycobacterium tuberculosis (Mtb) infection. Here we analyzed the protective efficacy of BCG against Mtb challenges 21 or 120 days after vaccination. Only after 120 days post-vaccination were mice able to efficien...

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Bibliographic Details
Main Author: Cruz, Andrea Patrícia Ribeiro (author)
Other Authors: Torrado, Egídio (author), Carmona, Jenny (author), Fraga, Alexandra G. (author), Costa, Patrício Soares (author), Rodrigues, Fernando (author), Appelberg, Rui (author), Neves, Margarida Correia (author), Cooper, Andrea M. (author), Saraiva, Margarida (author), Pedrosa, Jorge (author), Castro, António G. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Tuberculosis
BCG vaccination
Multifunctional CD4+ T cells
Effector CD4+ T cells
Memory CD4+ T cells
Memory CD4(+) T
Effector CD4<sup>+</sup> T cells
Memory CD4<sup>+</sup> T cells
Multifunctional CD4<sup>+</sup> T cells
Science & Technology
Online Access:http://hdl.handle.net/1822/32920
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32920

Internet

http://hdl.handle.net/1822/32920

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