Microfluidic-based platform to mimic the in vivo peripheral administration of neurotropic nanoparticles

Aim: Propose a nanoparticle for neuron-targeted retrograde gene delivery and describe a microfluidic-based culture system to provide insight into vector performance and safety. Methods: Using compartmentalized neuron cultures we dissected nanoparticle bioactivity upon delivery taking advantage of (q...

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Bibliographic Details
Main Author: Lopes, C (author)
Other Authors: Gomes, C (author), Neto, E (author), Sampaio, P (author), Aguiar, P (author), Pêgo, AP (author)
Format: article
Language:eng
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10216/120744
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/120744