Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
Deregulation of proteostasis is a main feature of many age-related diseases, often leading to the accumulation of toxic oligomers and insoluble protein aggregates that accumulate intracellularly or in the extracellular space. To understand the mechanisms whereby toxic or otherwise unwanted proteins...
| Main Author: | |
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| Other Authors: | , , , , , , |
| Format: | article |
| Language: | eng |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://doi.org/10.1371/journal.pone.0223790 |
| Country: | Portugal |
| Oai: | oai:run.unl.pt:10362/85727 |