The carboxylic acid transporters Jen1 and Jen2 affect the architecture and fluconazole susceptibility of Candida albicans biofilm in the presence of lactate

Candida albicans has the ability to adapt to different host niches, often glucose-limited but rich in alternative carbon sources. In these glucose-poor microenvironments, this pathogen expresses JEN1 and JEN2 genes, encoding carboxylate transporters, which are important in the early stages of infect...

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Bibliographic Details
Main Author: Alves, Rosana (author)
Other Authors: Mota, Sandra (author), Silva, Sónia (author), F. Rodrigues, Célia (author), P. Brown, Alistair J. (author), Henriques, Mariana (author), Casal, Margarida (author), Paiva, Sandra (author)
Format: article
Language:eng
Published: 2019
Subjects:
Adaptation, Physiological
Antifungal Agents
Biofilms
Biofouling
Candida albicans
Carboxylic Acids
Cellular Microenvironment
Drug Resistance, Fungal
Fluconazole
Fungal Proteins
Glucose
Lactic Acid
Monocarboxylic Acid Transporters
Online Access:http://hdl.handle.net/10400.22/14499
Country:Portugal
Oai:oai:recipp.ipp.pt:10400.22/14499

Internet

http://hdl.handle.net/10400.22/14499

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