Cdk Activity Couples Epigenetic Centromere Inheritance to Cell Cycle Progression

Centromeres form the site of chromosome attachment to microtubules during mitosis. Identity of these loci is maintained epigenetically by nucleosomes containing the histone H3 variant CENP-A. Propagation of CENP-A chromatin is uncoupled from DNA replication initiating only during mitotic exit. We no...

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Bibliographic Details
Main Author: Silva, Mariana C.C. (author)
Other Authors: Bodor, Dani L. (author), Stellfox, Madison E. (author), Martins, Nuno M.C. (author), Hochegger, Helfrid (author), Foltz, Daniel R. (author), Jansen, Lars E.T. (author)
Format: article
Language:eng
Published: 2016
Subjects:
Autoantigens
Blotting, Western
CDC2 Protein Kinase
Cell Cycle
Cell Division
Centromere
Chromatin
Chromosomal Proteins, Non-Histone
Cyclin-Dependent Kinase 2
Flow Cytometry
Fluorescent Antibody Technique
G1 Phase
HeLa Cells
Humans
Mitosis
Phosphorylation
Epigenomics
Online Access:http://hdl.handle.net/10400.7/616
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/616

Internet

http://hdl.handle.net/10400.7/616

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