Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone-starch scaffold and the in vitro development of vascularization

The reconstruction of bone defects based on cell-seeded constructs requires a functional microvasculature that meets the metabolic demands of the engineered tissue. Therefore, strategies that augment neovascularization need to be identified. We propose an in vitro strategy consisting of the simultan...

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Bibliographic Details
Main Author: Santos, Marina I. (author)
Other Authors: Unger, Ronald E. (author), Sousa, R. A. (author), Reis, R. L. (author), Kirkpatrick, C. James (author)
Format: article
Language:eng
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1822/20640
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/20640