Role of p53 in different colorectal carcinogenesis pathways Is it relevant for clinical practice?

p53 is a protein that regulates cell cycle, apoptosis and genomic stability. It is thought to be responsible for the progression from dysplasia to colorectal cancer (CRC), in sporadic cancers. In Inflammatory Bowel Disease (IBD) patients, CRC can occur as a result of the chronic inflammatory state o...

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Detalhes bibliográficos
Autor principal: Sacramento, Maria Luísa Noites (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10400.6/10752
País:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/10752