Role of p53 in different colorectal carcinogenesis pathways Is it relevant for clinical practice?

p53 is a protein that regulates cell cycle, apoptosis and genomic stability. It is thought to be responsible for the progression from dysplasia to colorectal cancer (CRC), in sporadic cancers. In Inflammatory Bowel Disease (IBD) patients, CRC can occur as a result of the chronic inflammatory state o...

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Bibliographic Details
Main Author: Sacramento, Maria Luísa Noites (author)
Format: masterThesis
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.6/10752
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/10752