N1- and C6-substituted adenines : a regioselective and efficient synthesis

New and efficient methods for the synthesis of N1-substituted and C6-substitued adenines were developed from the easily accessible 5-aminoimidazole-4-carboxamidines. Condensation of these compounds with triethyl orthoformate led to the selective synthesis of the N1-substituted adenines. Regioselecti...

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Bibliographic Details
Main Author: Senhorães, Nádia (author)
Other Authors: Costa, A. Luísa (author), Silva, Deolinda (author), Proença, M. Fernanda R. P. (author), Dias, Alice (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1822/26896
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/26896