Dioctadecyldimethylammonium:monoolein nanocarriers for efficient in vitro gene silencing

This study describes a novel liposomal formulation for siRNA delivery, based on the mixture of the neutral lipid monoolein (MO) and cationic lipids of the dioctadecyldimethylammonium (DODA) family. The cationic lipids dioctadecyldimethylammonium bromide (DODAB) and chloride (DODAC) were compared in...

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Bibliographic Details
Main Author: Oliveira, Ana Cristina Norberto Gonçalves (author)
Other Authors: Martens, Thomas (author), Raemdonck, Koen (author), Adati, Renata (author), Feitosa, Eloi (author), Botelho, C. M. (author), Gomes, Andreia (author), Braeckmans, Kevin (author), Real Oliveira, M. Elisabete C.D. (author)
Format: article
Language:eng
Published: 2014
Subjects:
counterion
gene silencing
liposomes
monoolein
siRNA delivery
Science & Technology
Online Access:http://hdl.handle.net/1822/32877
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32877

Internet

http://hdl.handle.net/1822/32877

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