Dioctadecyldimethylammonium:monoolein nanocarriers for efficient in vitro gene silencing

This study describes a novel liposomal formulation for siRNA delivery, based on the mixture of the neutral lipid monoolein (MO) and cationic lipids of the dioctadecyldimethylammonium (DODA) family. The cationic lipids dioctadecyldimethylammonium bromide (DODAB) and chloride (DODAC) were compared in...

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Detalhes bibliográficos
Autor principal: Oliveira, Ana Cristina Norberto Gonçalves (author)
Outros Autores: Martens, Thomas (author), Raemdonck, Koen (author), Adati, Renata (author), Feitosa, Eloi (author), Botelho, C. M. (author), Gomes, Andreia (author), Braeckmans, Kevin (author), Real Oliveira, M. Elisabete C.D. (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
counterion
gene silencing
liposomes
monoolein
siRNA delivery
Science & Technology
Texto completo:http://hdl.handle.net/1822/32877
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32877

Texto Completo

http://hdl.handle.net/1822/32877

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