Glycation potentiates neurodegeneration in models of Huntington's disease

Protein glycation is an age-dependent posttranslational modification associated with several neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. By modifying aminogroups, glycation interferes with folding of proteins, increasing their aggregation potential. Here, w...

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Detalhes bibliográficos
Autor principal: Miranda, Hugo Vicente (author)
Outros Autores: Gomes, Marcos Antonio (author), Branco-Santos, Joana (author), Breda, Carlo (author), Lazaro, Diana F (author), Lopes, Lusa Vaqueiro (author), Herrera, Federico (author), Giorgini, Flaviano (author), Outeiro, Tiago F (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
SDG 3 - Good Health and Well-being
Texto completo:http://hdl.handle.net/10362/22380
País:Portugal
Oai:oai:run.unl.pt:10362/22380

Texto Completo

http://hdl.handle.net/10362/22380

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