Testing the therapeutic potential of doxycycline in a drosophila melanogaster model of Alzheimer disease

Therapies for Alzheimer disease that reduce the production of pathogenic amyloid beta (A beta) peptides have been associated with a range of unwanted effects. For this reason, alternative strategies that promote the clearance of the peptide by preventing its aggregation and deposition in the brain h...

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Bibliographic Details
Main Author: Costa, Rita (author)
Other Authors: Speretta, Elena (author), Crowther, Damian C. (author), Cardoso, Isabel (author)
Format: article
Language:eng
Published: 2021
Subjects:
Amyloid beta-peptide
Parkinsons-disease
Mouse model
A-beta
Huntingtons-disease
Lateral-sclerosis
Rat model
In-vitro
Minocycline
Tetracyclines
Online Access:http://hdl.handle.net/10400.22/18579
Country:Portugal
Oai:oai:recipp.ipp.pt:10400.22/18579

Internet

http://hdl.handle.net/10400.22/18579

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