IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy

Increased production of IL-10 has been frequently associated with augmented susceptibility to infection. However, the correlation between IL-10 activity and susceptibility to mycobacterial infection is still uncertain. Although studies using transgenic mice overexpressing IL-10 consistently showed a...

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Bibliographic Details
Main Author: Roque, Susana (author)
Other Authors: Nobrega, Claudia (author), Appelberg, Rui (author), Correia-Neves, M (author)
Format: article
Language:eng
Published: 2007
Subjects:
Animals
Antibiotics, Antitubercular
Antibodies, Blocking
Disease Susceptibility
Interferon-gamma
Interleukin-10
Interleukin-2 Receptor alpha Subunit
Leukosialin
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Mycobacterium Infections
Receptors, Interleukin-10
Spleen
Treatment Outcome
Mycobacterium avium
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/67763
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67763

Internet

http://hdl.handle.net/1822/67763

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