Role of CFTR in Epithelial Differentiation by Functional Genomics

Cystic Fibrosis (CF) is caused by mutations in the CFTR gene. The relationship between CFTR and differentiation has been firmly documented. However, the mechanisms that regulate this relationship are still unclear. The aim of this work was to further characterize the differentiation defect in CF and...

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Detalhes bibliográficos
Autor principal: Sousa, Luís Miguel dos Santos (author)
Formato: doctoralThesis
Idioma:eng
Publicado em: 2021
Assuntos:
Fibrose Quística
KLF4
Diferenciação epitelial
AKT
EMT
Cystic Fibrosis
Epithelial differentiation
AKT signalling
Domínio/Área Científica::Ciências Naturais::Ciências Biológicas
Texto completo:http://hdl.handle.net/10451/48522
País:Portugal
Oai:oai:repositorio.ul.pt:10451/48522

Texto Completo

http://hdl.handle.net/10451/48522

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