Neuregulin-1 attenuates right ventricular diastolic stiffness in experimental pulmonary hypertension

We have previously shown that treatment with recombinant human neuregulin-1 (rhNRG-1) improves pulmonary arterial hypertension (PAH) in a monocrotaline (MCT)-induced animal model, by decreasing pulmonary arterial remodelling and endothelial dysfunction, as well as by restoring right ventricular (RV)...

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Bibliographic Details
Main Author: Adao, R (author)
Other Authors: Mendes Ferreira, P (author), Maia Rocha, C (author), Santos Ribeiro, D (author), Rodrigues, PG (author), Vidal Meireles, A (author), Monteiro Pinto, C (author), Pimentel, LD (author), Falcao Pires, I (author), De Keulenaer, GW (author), Leite Moreira, AF (author), Brás-Silva C (author)
Format: article
Language:eng
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10216/121393
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/121393