Evolution of the human immunodeficiency virus type 2 envelope in the first years of infection is associated with the dynamics of the neutralizing antibody response

Background: Differently from HIV-1, HIV-2 disease progression usually takes decades without antiretroviral therapy and the majority of HIV-2 infected individuals survive as elite controllers with normal CD4+ T cell counts and low or undetectable plasma viral load. Neutralizing antibodies (Nabs) are...

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Bibliographic Details
Main Author: Rocha, Cheila (author)
Other Authors: Calado, Rita (author), Borrego, Pedro (author), Marcelino, José M. (author), Bártolo, Inês (author), Rosado, Lino (author), Cavaco-Silva, Patrícia (author), Gomes, Perpétua (author), Família, Carlos (author), Quintas, Alexandre (author), Skar, Helena (author), Leitner, Thomas (author), Barroso, Helena (author), Taveira, Nuno (author)
Format: article
Language:eng
Published: 2018
Subjects:
Escape from neutralization
Evolution of the neutralizing antibody response
Molecular evolution
Tropism
Vertical HIV-2 infection
Virology
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:https://doi.org/10.1186/1742-4690-10-110
Country:Portugal
Oai:oai:run.unl.pt:10362/30200

Internet

https://doi.org/10.1186/1742-4690-10-110

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