Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors
Brain defective cholesterol homeostasis has been associated with neurologic diseases, such as Alzheimer's and Huntington's disease. The elimination of cholesterol from the brain involves its conversion into 24(S)-hydroxycholesterol by CYP46A1, and the efflux of this oxysterol across the bl...
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| Other Authors: | , , , , , |
| Format: | article |
| Language: | eng |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10451/21154 |
| Country: | Portugal |
| Oai: | oai:repositorio.ul.pt:10451/21154 |