Phosphorylated silk fibroin matrix for methotrexate release

Silk-based matrix was produced for delivery of a model anticancer drug, methotrexate (MTX). The calculation of net charge of silk fibroin and MTX was performed to better understand the electrostatic interactions during matrix formation upon casting. Silk fibroin films were cast at pH 7.2 and pH 3.5....

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Detalhes bibliográficos
Autor principal: Volkov, Vadim (author)
Outros Autores: Sárria, M. P. (author), Gomes, A. C. (author), Paulo, Artur Cavaco (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/1822/32905
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32905