Adverse outcome pathways induced by 3,4‑dimethylmethcathinone and 4‑methylmethcathinone in differentiated human SH‑SY5Y neuronal cells

Cathinones (β-keto amphetamines), widely abused in recreational settings, have been shown similar or even worse toxicological profile than classical amphetamines. In the present study, the cytotoxicity of two β-keto amphetamines [3,4-dimethylmethcathinone (3,4-DMMC) and 4-methylmethcathinone (4-MMC)...

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Bibliographic Details
Main Author: Soares, Jorge (author)
Other Authors: Costa, Vera Marisa (author), Gaspar, Helena (author), Santos, Susana (author), Bastos, Maria de Lourdes (author)
Format: article
Language:eng
Published: 2021
Subjects:
Cathinones
METH
Toxicological pathways
Mitochondrial impairment
Oxidative stress
SH-SY5Y cells
Online Access:http://hdl.handle.net/10400.8/6139
Country:Portugal
Oai:oai:iconline.ipleiria.pt:10400.8/6139

Internet

http://hdl.handle.net/10400.8/6139

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