Improving the performance of nadolol stereoisomers' preparative separation using Chiralpak IA by SMB chromatography

The pseudobinary preparative separation of nadolol stereoisomers is performed by simulated moving bed chromatography (SMB). Using the Chiralpak IA adsorbent, a new 25:75:0.1 (v/v/v) methanol-acetonitrile-diethylamine solvent composition was selected to perform the experimental SMB separation and com...

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Detalhes bibliográficos
Autor principal: Arafah, Rami (author)
Outros Autores: Ribeiro, António E. (author), Rodrigues, Alírio (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Texto completo:http://hdl.handle.net/10198/9279
País:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/9279