Inhalable locust bean gum microparticles co-associating isoniazid and rifabutin: therapeutic assessment in a murine model of tuberculosis infection

Tuberculosis is a leading cause of death worldwide. Although the development of new antimycobacterial drugs is an obvious and necessary strategy to address the disease, improving the therapeutic performance of drugs already approved constitutes a valuable alternative approach. As the lung is the mos...

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Bibliographic Details
Main Author: Grenha, Ana (author)
Other Authors: Alves, Ana D. (author), Guerreiro, Filipa (author), Pinho, Jacinta (author), Simões, Sandra (author), Almeida, António José (author), Gaspar, Maria Manuela (author)
Format: article
Language:eng
Published: 2021
Subjects:
Tuberculosis
Pulmonary delivery
Locust bean gum
Spray-dried microparticles
Rifabutin; isoniazid
In vivo studies
Online Access:http://hdl.handle.net/10400.1/13683
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/13683

Internet

http://hdl.handle.net/10400.1/13683

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