Common polygenic variation contributes to risk of schizophrenia and bipolardisorder

Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%. We performed a genome-wide association study of 3,322 European individuals with schizophrenia and 3,587 controls. H...

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Detalhes bibliográficos
Autor principal: Purcell, S. M. (author)
Outros Autores: Wray, N. R. (author), Stone, J. L. (author), Visscher, P. M. (author), O'Donovan, M. C. (author), Sullivan, P. F. (author), Sklar, P. (author), Leader, S. M. (author), Ruderfer, D. M. (author), McQuillin, A. (author), Morris, D. W. (author), O'Dushlaine, C. T. (author), Corvin, A. (author), Holmans, P. A. (author), Macgregor, S. (author), Gurling, H. (author), Blackwood, D. H. (author), Craddock, N. J. (author), Gill, M. (author), Hultman, C. M. (author), Kirov, G. K. (author), Lichtenstein, P. (author), Muir, W. J. (author), Owen, M. J. (author), Pato, Carlos N. (author), Scolnick, E. M. (author), St Clair, D. (author), Williams, N. M. (author), Georgieva, L. (author), Nikolov, I. (author), Norton, N. (author), Williams, H. (author), Toncheva, D. (author), Milanova, V. (author), Helander, E. F. (author), Kenny, E. (author), Quinn, E. M. (author), Choudhury, K. (author), Datta, S. (author), Pimm, J. (author), Thirumalai, S. (author), Puri, V. (author), Krasucki, R. (author), Lawrence, J. (author), Quested, D. (author), Bass, N. (author), Crombie, C. (author), Fraser, G. (author), Leh, K. S. (author), Walker, N. (author), Black-wood, D. H. (author), McGhee, K. A. (author), Pickard, B. (author), Malloy, P. (author), Maclean, A. W. (author), Van Beck, M. (author), Pato, Michele T. (author), Medeiros, Helena (author), Middleton, Frank A. (author), Carvalho, Célia (author), Morley, C. (author), Fanous, Ayman H. (author), Conti, D. (author), Knowles, James A. (author), Ferreira, Carlos Paz (author), Macedo, António (author), Kirby, A. N. (author), Ferreira, M. A. (author), Daly, M. J. (author), Cham-bert, K. (author), Kuruvilla, F. (author), Gabriel, S. B. (author), Ardlie, K. (author), Moran, J. L. (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
Texto completo:http://hdl.handle.net/10400.3/3997
País:Portugal
Oai:oai:repositorio.uac.pt:10400.3/3997