A matrix pencil to the blind source separation of artifacts in 2D NMR spectra

Multidimensional proton nmr spectra of biomolecules dissolved in aqueous solutions are usually contaminated by an intense water artifact. We discuss the application of the generalized eigenvalue decomposition (GEVD) method using a matrix pencil to solve the blind source separation problem of removin...

ver descrição completa

Detalhes bibliográficos
Autor principal: Stadlthanner, K. (author)
Outros Autores: Theis, F. J. (author), Lang, E. W. (author), Tomé, A. M. (author), Gronwald, W. (author), Kalbitzer, H.-R. (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Blind source separation
Generalized eigendecomposition
Independent component analysis
Matrix pencil
2D NOESY spectra
Texto completo:http://hdl.handle.net/10773/5813
País:Portugal
Oai:oai:ria.ua.pt:10773/5813
Descrição
Resumo:Multidimensional proton nmr spectra of biomolecules dissolved in aqueous solutions are usually contaminated by an intense water artifact. We discuss the application of the generalized eigenvalue decomposition (GEVD) method using a matrix pencil to solve the blind source separation problem of removing the intense solvent peak and related artifacts. 2D NOESY spectra of simple solutes as well as dissolved proteins are studied.

Registos relacionados