Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis

Paracoccidioides brasiliensis is characterized by a multiple budding phenotype and a polymorphic cell growth, leading to the formation of cells with extreme variations in shape and size. Since Cdc42 is a pivotal molecule in establishing and maintaining polarized growth for diverse cell types, as wel...

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Bibliographic Details
Main Author: Almeida, A. J. (author)
Other Authors: Cunha, C. (author), Carmona, J. A. (author), Sampaio-Marques, B. (author), Carvalho, A. (author), Malavazi, I. (author), Steensma, H. Y. (author), Johnson, D. I. (author), Leão, Cecília (author), Logarinho, E. (author), Goldman, G. H. (author), Castro, António G. (author), Ludovico, Paula (author), Rodrigues, F. (author)
Format: article
Language:eng
Published: 2009
Subjects:
Animals
Cells, Cultured
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Fungal
Host-Pathogen Interactions
Macrophages
Mice
Mice, Inbred C57BL
Paracoccidioides
Paracoccidioidomycosis
Phagocytosis
RNA, Antisense
Virulence
cdc42 GTP-Binding Protein
Paracoccidioides brasiliensis
Dimorphic pathogenic fungus
Cdc42
Multiple budding
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/67588
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67588

Internet

http://hdl.handle.net/1822/67588

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