Multidrug-resistant bacteria compensate for the epistasis between resistances

Mutations conferring resistance to antibiotics are typically costly in the absence of the drug, but bacteria can reduce this cost by acquiring compensatory mutations. Thus, the rate of acquisition of compensatory mutations and their effects are key for the maintenance and dissemination of antibiotic...

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Bibliographic Details
Main Author: Moura de Sousa, Jorge (author)
Other Authors: Balbontín, Roberto (author), Durão, Paulo (author), Gordo, Isabel (author)
Format: article
Language:eng
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10400.7/748
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/748