DNFB activates MAPKs and upregulates CD40 in skin-derived dendritic cells

BACKGROUND: The intracellular mechanisms involved in the activation of DCs during sensitization in allergic contact dermatitis (ACD) are not known. OBJECTIVE: Here, we investigated the effect of a strong sensitizer, 2,4-dinitrofluorobenzene (DNFB) on the activity of MAPKs in a dendritic cell (DC) li...

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Bibliographic Details
Main Author: Matos, TJ (author)
Other Authors: Duarte, CB (author), Gonçalo, Margarida (author), Lopes, MC (author)
Format: article
Language:eng
Published: 2010
Subjects:
Dermatite de Contacto Alérgica
Células Dendríticas
Dinitrofluorobenzeno
Antigénio CD40
Online Access:http://hdl.handle.net/10400.4/754
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/754

Internet

http://hdl.handle.net/10400.4/754

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