An efficient synthetic access to new uracil-alditols bearing a porphyrin unit and biological assessment in prostate cancer cells

An efficient access to porphyrin derivatives bearing uracil-alditol moieties at the beta-pyrrolic position was developed. The synthetic strategy involved a hetero Diels-Alder reaction between uracil-alditol based ortho-quinodimethanes using 2-vinyl-5,10,15,20-tetraphenylporphyrin as the scaffold. Th...

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Bibliographic Details
Main Author: Dias, Cristina J. (author)
Other Authors: Sardo, Inês (author), Moura, Nuno M. M. (author), Felgueiras, Juliana (author), Neves, M. Graça P. M. S. (author), Fardilha, Margarida (author), Faustino, M. Amparo F. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Porphyrin derivatives
Uracil-alditols
Photodynamic therapy
Prostate cancer
Online Access:http://hdl.handle.net/10773/29393
Country:Portugal
Oai:oai:ria.ua.pt:10773/29393

Internet

http://hdl.handle.net/10773/29393

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