Role of monocarboxylate transporters in human cancers : state of the art

Monocarboxylate transporters (MCTs) belong to the SLC16 gene family, presently composed by 14 members. MCT1-MCT4 are proton symporters, which mediate the transmembrane transport of pyruvate, lactate and ketone bodies. The role of MCTs in cell homeostasis has been characterized in detail in normal ti...

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Detalhes bibliográficos
Autor principal: Pinheiro, Céline (author)
Outros Autores: Longatto Filho, Adhemar (author), Azevedo, João Silva (author), Casal, Margarida (author), Schmitt, Fernando C. (author), Baltazar, Fátima (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Monocarboxylate transporters
Cancer
Warburg effect
Lactate
Science & Technology
Texto completo:http://hdl.handle.net/1822/21367
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/21367

Texto Completo

http://hdl.handle.net/1822/21367

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