Role of monocarboxylate transporters in human cancers : state of the art

Monocarboxylate transporters (MCTs) belong to the SLC16 gene family, presently composed by 14 members. MCT1-MCT4 are proton symporters, which mediate the transmembrane transport of pyruvate, lactate and ketone bodies. The role of MCTs in cell homeostasis has been characterized in detail in normal ti...

Full description

Bibliographic Details
Main Author: Pinheiro, Céline (author)
Other Authors: Longatto Filho, Adhemar (author), Azevedo, João Silva (author), Casal, Margarida (author), Schmitt, Fernando C. (author), Baltazar, Fátima (author)
Format: article
Language:eng
Published: 2012
Subjects:
Monocarboxylate transporters
Cancer
Warburg effect
Lactate
Science & Technology
Online Access:http://hdl.handle.net/1822/21367
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/21367

Internet

http://hdl.handle.net/1822/21367

Similar Items