Immunogenetic predisposing factors for mesial temporal lobe epilepsy with hippocampal sclerosis

Purpose: Neuroinflammation appears as an important epileptogenic mechanism. Experimental and clinical studies have demonstrated an upregulation of pro-inflammatory cytokines such as IL-1β and TNF-α, in mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). Expression of these cytokines...

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Detalhes bibliográficos
Autor principal: Leal, Bárbara (author)
Outros Autores: Chaves, João (author), Carvalho, Cláudia (author), Bettencourt, Andreia (author), Brito, Cláudia (author), Boleixa, Daniela (author), Freitas, Joel (author), Brás, Sandra (author), Lopes, João (author), Ramalheira, João (author), Costa, Paulo (author), Silva, Berta (author), Martins Da Silva, António (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Adolescent
Adult
Aged
Case-Control Studies
Epilepsy, Temporal Lobe
Female
Genotype
HLA-DRB1 Chains
Hippocampus
Humans
Immunogenetics
Interleukin-1alpha
Male
Middle Aged
Polymorphism, Single Nucleotide
Sclerosis
Tumor Necrosis Factor-alpha
Young Adult
Causality
Determinantes da Saúde e da Doença
Doenças Genéticas
Texto completo:http://hdl.handle.net/10400.18/6258
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6258

Texto Completo

http://hdl.handle.net/10400.18/6258

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