Is serotonin receptor HTR1B implicated in mesial temporal lobe epilepsy development?

Background: Evidences from animal models have demonstrated that depletion of brain serotonin (5-HT), a neurotransmitter with a pivotal role in neurodevelopment and brain plasticity, lowers the threshold to induced seizures. It was also demonstrated that anti-epileptic drugs increase endogenous 5-HT...

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Bibliographic Details
Main Author: Leal, B. (author)
Other Authors: Barreira, A. (author), Chaves, J. (author), Carvalho, C. (author), Bettencourt, A. (author), Martins da Silva, A. (author), Costa, P.P. (author), Martins da Silva, B. (author)
Format: conferenceObject
Language:eng
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10400.18/2216
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2216