Revisiting the role of the mother centriole in centriole biogenesis

Centrioles duplicate once in each cell division cycle through so-called templated or canonical duplication. SAK, also called PLK4 (SAK/PLK4), a kinase implicated in tumor development, is an upstream regulator of canonical biogenesis necessary for centriole formation. We found that overexpression of...

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Detalhes bibliográficos
Autor principal: Rodrigues-Martins, A (author)
Outros Autores: Riparbelli, M (author), Callaini, G (author), Glover, D M (author), Bettencourt-Dias, M (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
Animals
Animals, Genetically Modified
Centrioles
Centrosome
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Embryonic Development
Female
Mitosis
Oocytes
Texto completo:http://hdl.handle.net/10400.7/955
País:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/955

Texto Completo

http://hdl.handle.net/10400.7/955

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