Developing a co-culture system for effective megakaryo/thrombopoiesis from umbilical cord blood hematopoietic stem/progenitor cells

Background aims. Platelet transfusion can be a life-saving procedure in different medical settings. Thus, there is an increasing demand for platelets, of which shelf-life is only 5 days. The efficient ex vivo biomanufacturing of platelets would allow overcoming the shortages of donated platelets. Me...

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Bibliographic Details
Main Author: Hatami, Javad (author)
Other Authors: Andrade, Pedro Z. (author), Alves de Matos, António Pedro (author), Djokovic, Dusan (author), Lilaia, Carla (author), Ferreira, Frederico Castelo (author), Cabral, Joaquim M. S. (author), da Silva, Cláudia L. (author)
Format: article
Language:eng
Published: 1000
Subjects:
cell-cell contact
hematopoietic stem/progenitor cells
megakaryocyte
platelet
serum-free medium
umbilical cord blood
Online Access:http://hdl.handle.net/10773/17792
Country:Portugal
Oai:oai:ria.ua.pt:10773/17792

Internet

http://hdl.handle.net/10773/17792

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