Cytotoxicity and chromosomal aberrations induced by acrylamide in V79 cells

Acrylamide (AA) is a suspected human carcinogen found to be generated during the heating of carbohydrate-rich foodstuffs. AA exhibits 'Michael-type' reactivity towards reduced glutathione (GSH), resulting in vivo in the urinary excretion of mercapturic acid conjugates. GSH is a key factor...

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Bibliographic Details
Main Author: Oliveira, Nuno G. (author)
Other Authors: Pingarilho, Marta (author), Martins, Celia (author), Fernandes, Ana Sofia (author), Vaz, Sofie (author), Martins, Vanda (author), Rueff, Jose (author), Gaspar, Jorge Francisco (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21491
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21491