Redefining the role of ectoderm in somitogenesis: a player in the formation of the fibronectin matrix of presomitic mesoderm

The absence of ectoderm impairs somite formation in cultured presomitic mesoderm (PSM) explants, suggesting that an ectoderm-derived signal is essential for somitogenesis. Here we show in chick that the standard enzymatic treatments used for explant isolation destroy the fibronectin matrix surroundi...

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Bibliographic Details
Main Author: Rifes, Pedro (author)
Other Authors: Carvalho, Lara (author), Lopes, Catarina (author), Andrade, Raquel P. (author), Rodrigues, Gabriela (author), Palmeirim, Isabel (author), Thorsteinsdóttir, Sólveig (author)
Format: article
Language:eng
Published: 2007
Subjects:
Animals
Cell Separation
Cells, Cultured
Chick Embryo
Collagenases
Ectoderm
Extracellular Matrix
Fibronectins
Mesoderm
Models, Biological
Pancreatin
Somites
Tissue Culture Techniques
Embryonic Development
somitogenesis
fibronectin
presomitic mesoderm
integrins
chick
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/67756
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67756

Internet

http://hdl.handle.net/1822/67756

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