New Methodology for the Synthesis of 3-Substituted Coumarins via Pd-Catalyzed Site-Selective Cross-Coupling Reactions

A particularly useful, easy and concise synthesis of diversified 3-aryl coumarin was achieved using Heck coupling reactions between coumarin and aryliodides. The introduction of the aryl moiety occurred regioselective at the 3-position of the heteroaromatic ring.

Bibliographic Details
Main Author: Martins, Sérgio (author)
Other Authors: Branco, Paula (author), Torre, Maria (author), Sierra, Miguel (author), Pereira, António (author)
Format: article
Language:por
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10174/3464
Country:Portugal
Oai:oai:dspace.uevora.pt:10174/3464