Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites

A number of valproate adverse reactions are due to its interference with several metabolic pathways, including that of fatty acid oxidation. In order to resolve which mitochondrial enzymes of fatty acid oxidation are inhibited by which VPA intermediates w

Detalhes bibliográficos
Autor principal: Silva, MFB (author)
Outros Autores: Ruiter, JPN (author), IJlst, L (author), Allers, P (author), ten Brink, HJ (author), Jakobs, C (author), Duran, M (author), de Almedia, IT (author), Wander, RJA (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/10451/21329
País:Portugal
Oai:oai:repositorio.ul.pt:10451/21329