Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites

A number of valproate adverse reactions are due to its interference with several metabolic pathways, including that of fatty acid oxidation. In order to resolve which mitochondrial enzymes of fatty acid oxidation are inhibited by which VPA intermediates w

Bibliographic Details
Main Author: Silva, MFB (author)
Other Authors: Ruiter, JPN (author), IJlst, L (author), Allers, P (author), ten Brink, HJ (author), Jakobs, C (author), Duran, M (author), de Almedia, IT (author), Wander, RJA (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21329
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21329