Human mTOR transcript contains an IRES element that guarantees its expression and function under global translation impairing conditions
Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals from the cellular nutrient- and energy-status, acting namely on the protein synthesis machinery. Due to its role in regulating protein synthesis, mTOR signaling, and consequently its deregulation, is...
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| Format: | lecture |
| Language: | eng |
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2017
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| Online Access: | http://hdl.handle.net/10400.18/3662 |
| Country: | Portugal |
| Oai: | oai:repositorio.insa.pt:10400.18/3662 |